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data-id="" >PubMedhttps://pubmed.ncbi.nlm.nih.gov/34240733Soluble (pro)renin receptor: a novel ligand for angiotensin II …网页2021年7月16日 · This commentary highlights the study entitled 'Soluble (pro)renin receptor induces endothelial dysfunction and hypertension in mice with diet-induced obesity via activation of angiotensin II type 1 receptor' presented by Fu et al. published in Clinical Science (Clin Sci (Lond) (2021) 135(6), https:/ …
发布时间：2024-06-02data-id="" >PubMedhttps://pubmed.ncbi.nlm.nih.gov/28509726Sodium butyrate suppresses angiotensin II-induced hypertension …网页The present study was aimed to investigate the role of NaBu in angiotensin II (Ang II)-induced hypertension and to further explore the underlying mechanism. ... Renal tissues, serum samples, and 24-h urine samples were collected to examine renal injury and the regulation of the (pro)renin receptor (PRR) and renin.
发布时间：2024-06-02data-id="" >AHA/ASA Journalshttps://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.111.188714Angiotensin II Infusion Model of Hypertension | Hypertension网页In the Ang II infusion model of hypertension, the temporal changes in central sympathetic outflow reflect the balance between the direct excitatory actions of Ang II on the brain and the indirect effects of pressure-mediated baroreflex activation to inhibit sympathetic outflow. Despite the possibility that Ang II may chronically increase RSNA ...
发布时间：2024-06-02data-id="" >PubMedhttps://pubmed.ncbi.nlm.nih.gov/30819554The (pro)renin receptor: an emerging player in hypertension …网页The (pro)renin receptor (PRR) is a multifunctional protein that is expressed in multiple organs. Binding of prorenin/renin to the PRR activates angiotensin II-dependent and angiotensin II-independent pathways. The PRR is also involved in autophagy and Wnt/ß catenin signaling, functions that are not contingent on prorenin binding.
发布时间：2024-06-02data-id="" >Naturehttps://www.nature.com/articles/s41569-023-00964-1Immune and inflammatory mechanisms in hypertension网页2024年1月3日 · Hypertension is a global health challenge, affecting >1.3 billion people worldwide, and the development of this condition is closely associated with inflammatory dysregulation and immune ...
发布时间：2024-06-02data-id="" >ScienceDirecthttps://www.sciencedirect.com/science/article/pii/S0269749117303019Diesel exhaust inhalation exposure induces pulmonary …网页2018年6月1日 · The levels of pro-inflammatory cytokines tumor necrosis factor (TNF-α), interleukin-6 (IL-6) and IL-13 produced by T helper 17 (Th17) and Th2 cells were markedly elevated in lung tissues of mice after DE inhalation exposure. ... Interleukin-6 overexpression induces pulmonary hypertension. Circ. Res., 104 (2) (2009), pp. 236-244. View in Scopus ...
发布时间：2024-06-02data-id="" >PubMedhttps://pubmed.ncbi.nlm.nih.gov/32738302A high salt diet induces tubular damage associated with a pro ...网页2020年11月1日 · However, little is known about the effects of HSD on renal function independently of the development of hypertension. To address the hypothesis that HSD induces renal injuries even without changes in blood pressure, BALB/c mice were fed for 7 days with chow with a high salt content (0.3-8%).
发布时间：2024-06-02data-id="" >PubMedhttps://pubmed.ncbi.nlm.nih.gov/37290790TLR7/8 activation induces autoimmune vasculopathy and …网页2023年7月20日 · TLR7/8 activation induces autoimmune vasculopathy and causes severe pulmonary arterial hypertension Eur Respir J. 2023 Jul 20;62(1):2300204. doi: 10.1183/13993003.00204-2023. Print 2023 Jul. Authors Fu-Chiang Yeh 1 ... Hypertension, Pulmonary* / etiology
发布时间：2024-06-02